陈强的人物生平

1994年3月于日本东北大学药学部药品物理化学专业获得药学博士学位。现任南开大学特聘教授，博士生导师。个人学习和工作经历：1980.09－1984.07南开大学化学系物理化学专业，获得理学学士学位；1988.04－1994.03日本东北大学药学部药品物理化学专业，获得药学硕士、药学博士学位；1996.03－2001.04日本东北大学药学研究科任教并完成在职博士后研究，成为东北大学药学部创建以来第一位外籍教员；2001.05－至今任教于南开大学生命科学学院，并创建生物传感器实验室。兼任生物活性材料教育部重点实验室副主任，建立了新型诊断材料领域，开展了分子间相互作用和分子识别的新型分析技术、中药作用机理及方剂配伍规律研究新方法的构建，功能微生物及其在环保、农业中的应用等跨学科的研究。目前的主要研究方向：生物电分析化学、生物医学传感技术、中药药理及药物分析研究成果：在纳米新材料光电化学技术、高性能纳米结构固定化酶电极制备技术、分子间相互作用和分子识别的新型分析技术、中药作用机理及方剂配伍规律研究新方法的构建等方向取得了显著成果。在国内外核心刊物发表论文80余篇，其中40余篇被SCI、EI收录，已授权专利6项，申请中专利1项。主持和分担了国家自然科学基金、“863”计划、教育部、天津市等科研项目十余项，研究成果获1997年日本文部省奖励研究A和2005年度天津市自然科学二等奖（编号2005ZR-2-011-R1）。研究生培养：获2006年度南开大学“敬业”奖教金一等奖。指导博士研究生中有两名分别于2005、2006年获得“南开十杰”称号，所指导研究生多次获得“南开大学优秀硕士毕业论文”及“南开大学优秀毕业生”奖励。为研究生开设三门课程：“物理化学在生命体系中的应用”（硕士生）、“生物电化学”（博士生）、“生物传感器的原理与技术”（博士生）。硕士生、博士生招生专业：生物化学与分子生物学、动物学代表性文章目录：1.ZixiaZhao,MingqiangQiao,FengYin,BinShao,BaoyanWu,YanyanWang,XinshengWang,XiaQin,ShaLi,LeiYu,QiangChen.Amperometricglucosebiosensorbasedonself-assemblyhydrophobinwithhighefficiencyofenzymeutilization.Biosensors&Bioelectronics,2007,22:3021-3027(SCI,IF5.061)2.BaoyanWu,ShihuaHou，FengYin,ZixiaZhao,YanyanWang,XinshengWang,QiangChen.Amperometricglucosebiosensorbasedonmultilayerfilmsvialayer-by-layerself-assemblyofmulti-wallcarbonnanotubes,goldnanoparticlesandglucoseoxidaseonthePtelectrode.Biosensors&Bioelectronics,2007,22:2854-2860(SCI,IF5.061)3.BaoyanWu,ShihuaHou,FengYin,JingLi,ZixiaZhao,JiadongHuang,QiangChen.AmperometricGlucoseBiosensorBasedonLayer-by-layerAssemblyofMultilayerFilmsComposedofChitosan,GoldNanoparticalsandGlucoseOxidaseModefiedPtElectrode.Biosensors&Bioelectronics,2007,22:838-844(SCI,IF5.061)4.HaibinShi,YuYang,JiadongHuang,ZixiaZhao,XinhuaXu,Jun-ichiAnzai,TetsuoOsa,QiangChen.AmperometricCholineBiosensorsPreparedbyLayer-by-layerDepositionofCholineOxidaseonthePrussianBlue-ModifiedPlatinumElectrode.Talanta,2006,70:852-858(SCI,IF3.374)5.WUBao-Yan,LIJing,HUANGJia-Dong,WangYanyan,YinHuijun,ChenKeji,CHENQiang.Realtimekineticanalysisoftheinteractionbetweeninterleukin-1αandsolubleinterleukin-1receptorusingaresonantmirrorbiosensor.AnalyticaChimicaActa,2006,557:106-110(SCI,IF3.186)主要学术论文韩松岩,刘东波,黄亮,王深琪,刘清平,陈强.Monitoringadsorptioninsituandkineticstudiesoflow-densitylipoproteinontocholesterolmodifieddextranusingqua.CHEMICALJOURNALOFCHINESEUNIVERSITIES-CHINESE26-6-1166.2005-1-1李静,黄加栋,吴宝艳,陈强.EffectsofpropylgallateoninteractionbetweenTNF-alphaandsTNFR-Iusinganaffinitybiosensor.ACTAPHARMACOLOGICASINICA26-10-1212.2005-1-1史海滨，赵紫霞,宋昭,黄加栋,杨钰,陈强.Fabricatingofacetylcholinebiosensorbyalayer-by-layerdepositiontechniquefordeterminingtrichlorfon.ELECTROANALYSIS17-14-1285.2005-1-1陈强,韩君,史海滨,吴宝艳,许鑫华.UseofChitosanfordevelopinglayer-by-layermultilayerthinfilmscontainingglucoseoxidaseforbiosensorapplications.SensorLettersv2-n2-p102-105.2005-1-1史海滨,宋昭,黄加栋,杨钰,赵紫霞,陈强.Effectsofthetypeofpolycationinthecoatingfilmspreparedbyalayer-by-layerdepositiontechniqueonthepropertiesofamperometriccholinesensors.SensorsandActuators,B:Chemicalv109-n2-p341-347.2005-1-1史海滨,宋昭,黄加栋,杨钰,赵紫霞,陈强.Effectsofthetypeofpolycationontheamperometricresponseofcholinebiosensorspreparedbyalayer-by-layerdepositiontechnique.MaterialsScienceandEngineeringCv25-n4-p433-435.2005-1-1吴宝艳,许鑫华,史海滨,韩松岩,宋岩、黄亮,陈强.Effectofcelluloseacetatediffusionrestrictingmembraneontheglucosebiosensor.TianjinDaxueXuebao(ZiranKexueyuGongchengJishuBan)/JournalofTianjinUniversityScienceandTechnologyv38-n6-p513-517.2005-1-1尹峰;赵紫霞;吴宝艳;王新胜;王艳艳;陈强.Glucosebiosensorbasedonlayer-by-layerassemblyofmulti-walledcarbonnanotubesandpolyallylamine.CHINESEJOURNALOFANALYTICALCHEMISTRY35-7-1021-1024.2007-1-1刘强;许鑫华;张春怀;陈强.Electrochemicaldepositionofcompositefilmscomposedofpolyanilineandchitosanforbiosensorapplications.SENSORLETTERS5-2-459-462.2007-1-1赵紫霞;乔明强;尹峰;邵兵;吴宝艳;王艳艳;王新胜;秦霞;李莎;于雷;陈强.Amperometricglucosebiosensorbasedonself-assemblyhydrophobinwithhighefficiencyofenzymeutilization.BIOSENSORS&BIOELECTRONICS22-12-3021-3027.2007-1-1吴宝艳;侯识华;尹峰;赵紫霞;王艳艳;王新胜;陈强.Amperometricglucosebiosensorbasedonmultilayerfilmsvialayer-by-layerself-assemblyofmulti-wallcarbonnanotubes,goldnanoparticlesandglucoseoxidaseonthePtelectrode.BIOSENSORS&BIOELECTRONICS22-12-2854-2860.2007-1-1刘东波;贺秉军;韩松岩;王申奇;刘清平;Jun-ichi,A;Osa,T;陈强.Anadsorptionbehavioroflow-densitylipoproteinontocholesterol-modifieddextranstudiedbyaquartzcrystalmicrobalance.MATERIALSSCIENCE&ENGINEERINGC-BIOMIMETICANDSUPRAMOLECULARSYSTEMS27-4-665-669.2007-1-1黄加栋;宋昭;李静;杨钰;史海滨;吴宝艳;Anzai,JI;Osa,T;陈强.Ahighly-sensitiveL-lactateblosensorbasedonsol-gelfilmcombinedwithmulti-walledcarbonnanotubes(MWCNTs)modifiedelectrode.MATERIALSSCIENCE&ENGINEERINGC-BIOMIMETICANDSUPRAMOLECULARSYSTEMS27-1-29-34.2007-1-1吴宝艳;侯识华;尹峰;李静;赵紫霞;黄加栋;陈强.Amperometricglucosebiosensorbasedonlayer-by-layerassemblyofmultilayerfilmscomposedofchitosan,goldnanoparticlesandglucoseoxidasemodifiedPtelectrode.BIOSENSORS&BIOELECTRONICS22-6-838-844.2007-1-1宋昭;黄加栋;史海滨;吴宝艳;赵紫霞;陈强.Highlysensitivecholinebiosensorbasedonnanotubemodifiedptelectrodecombinedwithsol-gelimmobilization.CHINESEJOURNALOFANALYTICALCHEMISTRY34-7-910-914.2007-1-1Li,J;Huang,JD;Wu,BY;Song,Z;Chen,Q.Opticalbiosensoranalysisinstudyingpropylgallatebindingtoendothelin-1.SENSORLETTERS3-4-296.2006-1-1Chen,Q;Huang,JD;Yin,HJ;Chen,KJ;Osa,T.Theapplicationsofaffinitybiosensors:IAsysbiosensorandquartzcrystalmicrobalancetothestudyoninteractionbetweenPaeoniaeradix801andendothelin-1.SENSORSANDACTUATORSB-CHEMICAL115-1-116.2006-1-1Huang,JD;Yang,Y;Shi,HB;Song,Z;Zhao,ZX;Anzai,J;Osa,T;Chen,Q.Multi-walledcarbonnanotubes-basedglucosebiosensorpreparedbyalayer-by-layertechnique.MATERIALSSCIENCE&ENGINEERINGC-BIOMIMETICANDSUPRAMOLECULARSYSTEMS26-1-113.2006-1-1Song,Z;Huang,JD;Wu,BY;Shi,HB;Anzai,JI;Chen,Q.Amperometricaqueoussol-gelbiosensorforlow-potentialstablecholinedetectionatmulti-wallcarbonnanotubemodifiedplatinumelectrode.SENSORSANDACTUATORSB-CHEMICAL115-2-626.2006-1-1Shi,H;Yang,Y;Huang,JD;Zhao,ZX;Xu,XH;Anzai,J;Osa,T;Chen,Q.Amperometriccholinebiosensorspreparedbylayer-by-layerdepositionofcholineoxidaseonthePrussianblue-modifiedplatinumelectrode.TALANTA70-4-852.2006-1-1Wu,BY;Wang,YY;Li,J;Song,Z;Huang,JD;Wang,XS;Chen,Q.AnopticalbiosensorforkineticanalysisofsolubleInterleukin-1receptorIbindingtoimmobilizedInterleukin-1alpha.TALANTA70-3-485.2006-1-1Xu,XH;Ren,GL;Cheng,J;Liu,Q;Li,DG;Chen,Q.Layerbylayerself-assemblyimmobilizationofglucoseoxidaseontochitosan-graft-polyanilinepolymers.JOURNALOFMATERIALSSCIENCE41-10-3147.2006-1-1Wu,Bao-Yan;Li,Jing;Huang,Jia-Dong;Wang,Yan-Yan;Yin,Hui-Jun;Chen,Ke-Ji;Chen,Qiang.Realtimekineticanalysisoftheinteractionbetweeninterleukin-1αandsolubleinterleukin-1receptorIusingaresonantmirrorbiosensor.AnalyticaChimicaActav557-n1-2-p106-110.2006-1-1Wu,Baoyan;Li,Jing;Shi,Haibin;Huang,Jiadong;Anzai,Junichi;Osa,Tetsuo;Chen,Qiang.Ferrocene-mediatedanti-interferingglucosebiosensorbasedonglutinandcelluloseacetate.HighTechnologyLettersv12-n3-p263-266.2006-1-1YanyanWang,XinshengWang,BaoyanWu,ZixiaZhao,FengYin,ShaLi,XiaQin,QiangChen.Dispersionofsingle-walledcarbonnanotubesinpoly(diallyldimethylammoniumchloride)forprepara.SensorsandActuatorsB李莎王艳艳赵紫霞秦霞王新胜吴宝艳陈强.基于纳米材料、聚电解质制备高性能乙醇生物传感器.分析化学36-2-227-230.2008-2-1秦霞　王艳艳　赵紫霞　王新胜　李莎　于敏　黄楠　苗智颖　陈强.层层自组装制备基于多壁碳纳米管的胆碱生物传感器.分析化学36-6-827-830.2008-6-1Bao-YanWu,Shi-HuaHou,LiangHuang,FengYin,Zi-XiaZhao,Jun-IchiAnzai,QiangChen.OrientedimmobilizationofimmunoglobulinGontothecuvettesurfaceoftheresonantmirrorbiosenso.MaterialsScienceandEngineeringC28-7-1065-1069.2008-8-1JiadongHuang,JingLi,YuYang,XinshengWang,BaoyanWu,QiangChen.DevelopmentofanamperometricL-lactatebiosensorbasedonL-lactateoxidaseimmobilizedthroughsilicasol-gelfilmonmulti-walledcarbonnanotubes/platinumnanoparticlemodifiedglassycarbonelectrode.MaterialsScienceandEngineeringC28-7-1070-1075.2008-8-1Bao-YanWu,Shi-HuaHou,MinYu,XiaQin,ShaLi,QiangChen.Layer-by-layerassembliesofchitosan/multi-wallcarbonnanotubesandglucoseoxidaseforamperometricglucosebiosensorapplications.MaterialsScienceandEngineeringC29-1-346-349.2009-1-1于敏，王会才，秦霞，王新胜，昊宝艳，陈强.纳米银/半胱氨酸修饰葡萄糖生物传感器的研究.传感器与微系统27-10-24-26.2008-10-1XiaQin,HuicaiWang,XinshengWang,ShaLi,ZhiyingMiao,NanHuang,QiangChen.Amperometriccholinebiosensorsbasedonmulti-wallcarbonnanotubesandlayer-by-layerassemblyofmultilayerfilmscomposedofPoly(diallyldimethylammoniumchloride)andcholineoxidase.MaterialsScienceandEngineering:CZi-XiaZhao,Hui-CaiWang,XiaQin,Xin-ShengWang,Ming-QiangQiao,Jun-ichiAnzaib,QiangChen.Self-assembledfilmofhydrophobinsongoldsurfaceanditsapplicationtoelectrochemicalbiosensing.ColloidsandSurfacesB:BiointerfacesWeiZhao,HuicaiWang,XiaQin,XinshengWang,ZixiaZhao,ZhiyingMiao,LiliChen,MiaomiaoShan,YuxinFang,QiangChen.Anovelnonenzymatichydrogenperoxidesensorbasedonmulti-wallcarbonnanotube/silvernanoparticlenanohybridsmodifiedgoldelectrode.TalantaHuicaiWang,XinshengWang,XiaoqingZhang,XiaQin,ZixiaZhao,ZhiyingMiao,NanHuang,QiangChen.Anovelglucosebiosensorbasedontheimmobilizationofglucoseoxidaseontogoldnanoparticles-modifiedPbnanowires.BiosensorsandBioelectronicsShaLi,YanyanWang,ZixiaZhao,XiaQin,XinshengWang,MinYu,ZhiyingMiao,BaoyanWu,QiangChen.AmperometricEthanolBiosensorBasedonLayer-by-LayerDepositionofAlcoholOxidaseonthePlatinum.SensorlettersXiaQin,HuicaiWang,XinshengWang,ZhiyingMiao,LiliChen,WeiZhao,MiaomiaoShan,QiangChen.Amperometricbiosensorsbasedongoldnanoparticles-decoratedmultiwalledcarbonnanotubespoly(diallyldimethylammoniumchloride)biocompositeforthedeterminationofcholine.SensorsandActuatorsB陈丽丽,王会才,秦霞,王新胜,赵紫霞,苗智颖,赵薇,单苗苗,陈强.层层自组装技术制备PDDA-多壁碳纳米管-胆碱生物传感器.分析化学ZixiaZhao,QiangChen,Jun-ichiANZAI.Horseradishperoxidasemicrocapsulesbasedonlayer-by-layerpolyelectrolytedeposition.JournalofEnvironmentalSciences21-supplement1-YanyanWang,QiangChen,XiangqunZeng.Potentiometricbiosensorforstudyinghydroquinonecytotoxicityinvitro.BiosensorsandBioelectronics